1,8-Dihydroxy-3-methylanthraquinone
1,8-Dihydroxy-3-methylanthraquinone (CAS: 481-74-3), also known as Chrysophanic acid, is a naturally occurring anthraquinone with the molecular formula C15H10O4 and a molecular weight of 254.24 g/mol. This compound is recognised for its biological activities, including potential anticancer properties and antiviral research. It serves as a valuable building block in chemical synthesis and is of interest in cell biology and nutrition research.
- IUPAC
- Chrysophanic acid
- Synonyms
- Chrysophanic acid

Anticancer Research
Chrysophanic acid is utilised in studies investigating anticancer activity, particularly in EGFR-overexpressing human colon cancer cells.
Antiviral Studies
This compound has been used to examine the inhibition of poliovirus types 2 and 3 replication <i>in vitro</i>.
Chemical Synthesis
As an organic building block, 1,8-Dihydroxy-3-methylanthraquinone is a useful intermediate in the synthesis of more complex molecules.
Phytochemical Research
Found naturally in sources like Aloe Vera, it is studied for its properties as a phytochemical.
| Molecular weight | 254.24 |
|---|---|
| Empirical formula | C15H10O4 |
| Assay | 98% |
| Application | Chrysophanic acid, a natural anthraquinone, is used to study anticancer activity in EGFR-overexpressing SNU-C5 human colon cancer cells 1. It is also used to study the inhibition of replication of poliovirus types 2 and 3 (Picornaviridae) in vitro 2. |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
Precautionary statements
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... ELA2(1991) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1,8-Dihydroxy-3-methylanthraquinone used for?
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1,8-Dihydroxy-3-methylanthraquinone, also known as Chrysophanic acid, is used in research for its potential anticancer and antiviral activities, and as an organic building block in chemical synthesis.
What is the CAS number and formula for 1,8-Dihydroxy-3-methylanthraquinone?
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The CAS number is 481-74-3 and the empirical formula (Hill notation) is C15H10O4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1,8-Dihydroxy-3-methylanthraquinone with an assay of 98%. This product is intended for research and laboratory use and is not supplied as USP, BP, EP, or pharmacopoeia grade.
How should 1,8-Dihydroxy-3-methylanthraquinone be handled safely?
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1,8-Dihydroxy-3-methylanthraquinone is a warning substance that causes skin and serious eye irritation. Handle with appropriate personal protective equipment including a dust mask (type N95 US), eyeshields, and gloves. Ensure good ventilation. In case of contact, follow precautionary statements P305 + P351 + P338.
Is this chemical packed, shipped, or exported by TSS?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 1,8-Dihydroxy-3-methylanthraquinone.
How can I request a sample or a quote for 1,8-Dihydroxy-3-methylanthraquinone?
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To request a sample or a quote, please contact the Tech Serve Solutions sales team through our website or by calling us directly.
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