1,4-Diiodobenzene
1,4-Diiodobenzene (CAS 624-38-4) is an organoiodine compound with the molecular formula C6H4I2. This white to off-white crystalline solid serves as a valuable building block in organic synthesis. Its structure, featuring two iodine atoms on a benzene ring, makes it suitable for various coupling reactions and the construction of complex molecular architectures, including polymers and natural product analogues.
- Synonyms
- C6H4I2
Organic Synthesis Building Block
1,4-Diiodobenzene is employed in the synthesis of complex organic molecules. It has been utilized in the total synthesis of biologically active compounds such as martinellic acid, a bradykinin receptor antagonist.
Cross-Coupling Reactions
This compound is a precursor for preparing substituted aromatic systems via palladium- or copper-catalyzed cross-coupling reactions. It has been used in the preparation of 1,4-bis(p-R-phenylethynyl)benzenes.
Polymer Synthesis
1,4-Diiodobenzene serves as a starting material for the synthesis of extended conjugated systems. It is used in the preparation of oligo(1,4-phenylene ethynylene)s and in surface-mediated synthesis of polyphenylene lines.
| Molecular weight | 329.90 |
|---|---|
| Empirical formula | C6H4I2 |
| Assay | 99% |
| Boiling point | 285 °C(lit.) |
| Application | 1,4-Diiodobenzene was used in:• total synthesis of martinellic acid, a naturally occurring bradykinin receptor antagonist1• preparation of 1,4-bis(p-R-phenylethynyl)benzenes via Pd11/Cu1catalyzed cross-coupling reaction2• synthesis of 1,4-diiodo-2,5-didodecylbenzene, starting reagent for the preparation of oligo(1,4-phenylene ethynylene)s3• surface-mediated synthesis of epitaxially aligned and separated polyphenylene lines on Cu(110) via Ullmann dehalogenation reaction4 |
| Melting point | 131-133 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1,4-Diiodobenzene used for?
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1,4-Diiodobenzene is primarily used as a building block in organic synthesis, particularly in cross-coupling reactions and the preparation of polymers and complex organic molecules like martinellic acid.
What are the CAS number and formula for 1,4-Diiodobenzene?
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The CAS number for 1,4-Diiodobenzene is 624-38-4, and its empirical formula (Hill notation) is C6H4I2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1,4-Diiodobenzene with a minimum purity of 99%. We do not represent this product as USP, BP, or EP grade.
What are the safety and handling precautions for 1,4-Diiodobenzene?
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1,4-Diiodobenzene is classified with WGK Germany 3. Handling requires appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. Refer to the Safety Data Sheet for comprehensive information.
How is 1,4-Diiodobenzene packed and exported?
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1,4-Diiodobenzene is carefully packed according to international shipping regulations and is available for global export by Tech Serve Solutions.
How can I request a quote or sample of 1,4-Diiodobenzene?
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To request a quote or a sample of 1,4-Diiodobenzene, please contact our sales team through the website or by phone.
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