1,4-Difluoro-2,5-dimethoxybenzene
1,4-Difluoro-2,5-dimethoxybenzene (CAS: 199866-90-5) is a fluorinated organic compound with the linear formula F₂C₆H₂(OCH₃)₂ and a molecular weight of 174.14 g/mol. It serves as a valuable building block in organic synthesis, particularly in the development of novel materials and pharmaceutical intermediates. Its specific difluoro and dimethoxy substitution pattern offers unique electronic and steric properties for chemical research and development.
- Synonyms
- 199866-90-5F2C6H2(OCH3)2

Organic Synthesis Intermediate
This compound is utilised as a key intermediate in multi-step organic syntheses. Its fluorinated aromatic structure makes it suitable for introducing specific functionalities into target molecules.
Materials Science Research
1,4-Difluoro-2,5-dimethoxybenzene can be employed in the synthesis of advanced materials, potentially including polymers or electronic components, where its electronic properties are advantageous.
Pharmaceutical and Agrochemical Development
The molecule's structure may be incorporated into the design and synthesis of new active pharmaceutical ingredients (APIs) or agrochemicals, leveraging the influence of fluorine atoms on biological activity.
| Molecular weight | 174.14 |
|---|---|
| Linear formula | F2C6H2(OCH3)2 |
| Assay | 99% |
| Melting point | 123-125 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1,4-Difluoro-2,5-dimethoxybenzene used for?
+
1,4-Difluoro-2,5-dimethoxybenzene is primarily used as a building block in organic synthesis for the development of pharmaceuticals, agrochemicals, and advanced materials.
What are the CAS number and formula for 1,4-Difluoro-2,5-dimethoxybenzene?
+
The CAS number is 199866-90-5, and its linear formula is F₂C₆H₂(OCH₃)₂.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 1,4-Difluoro-2,5-dimethoxybenzene with an assay of 99%. We do not represent this product as USP, BP, or EP grade.
What are the safety considerations for handling 1,4-Difluoro-2,5-dimethoxybenzene?
+
This compound is classified as a Warning with hazards H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Appropriate personal protective equipment including a dust mask (N95), eyeshields, and gloves should be used. Ensure adequate ventilation.
How is 1,4-Difluoro-2,5-dimethoxybenzene packed, shipped, and exported?
+
Tech Serve Solutions professionally packs, ships, and exports chemicals globally, adhering to all necessary regulations for safe and compliant transport.
How can I request a sample or quote for 1,4-Difluoro-2,5-dimethoxybenzene?
+
To request a sample or quote, please contact the Tech Serve Solutions sales team through our website or by phone, providing the product name and CAS number.
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis