1,4-Dibromo-2-fluorobenzene

CAS 1435-52-5Br2C6H3FChemical Synthesis

1,4-Dibromo-2-fluorobenzene (CAS 1435-52-5) is an aryl compound with the linear formula Br2C6H3F and a molecular weight of 253.89 g/mol. This organobromine and organofluorine chemical serves as a valuable building block in organic synthesis. Its specific substitution pattern makes it useful for introducing brominated and fluorinated phenyl moieties into more complex molecules, particularly in the fields of materials science and pharmaceutical research.

Synonyms: Br2C6H3F

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1,4-Dibromo-2-fluorobenzene (Br2C6H3F) — chemical structure, CAS 1435-52-5; Chemistry, fine chemical supplied by Tech Serve Solutions

ArylBuilding BlocksChemical SynthesisFluorinated Building BlocksHalogenated HydrocarbonsOrganic Building Blocks

01 /Applications

Organic Synthesis Intermediate

1,4-Dibromo-2-fluorobenzene is employed as a key intermediate in the synthesis of various organic compounds. Its bromine atoms can participate in cross-coupling reactions, while the fluorine atom influences the electronic properties of the resulting molecules.

Pharmaceutical Research

This compound can be utilized in the development of novel pharmaceutical agents. The presence of both bromine and fluorine offers unique opportunities for structure-activity relationship studies in drug discovery.

Materials Science

As a fluorinated aryl building block, it finds application in the synthesis of advanced materials, including polymers and organic electronic components, where its structural features can impart desired properties.

02 /Properties

Molecular weight	253.89
Linear formula	Br2C6H3F
Assay	98%
Boiling point	216 °C(lit.)
Melting point	33-36 °C(lit.)

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust, fume, gas or vapours
P305IF IN EYES

Protective equipment	dust mask type N95 (US), Eyeshields, Gloves
Flash point	102 °C / 215.6 °F
Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xi
Risk statements (R)	36/37/38
Safety statements (S)	26-36

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

1435-52-5

MDL number

MFCD00010603

PubChem substance

24858324

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 1,4-Dibromo-2-fluorobenzene used for?

1,4-Dibromo-2-fluorobenzene is primarily used as an intermediate in organic synthesis, particularly in the development of pharmaceuticals, agrochemicals, and advanced materials.

What is the CAS number and formula for 1,4-Dibromo-2-fluorobenzene?

The CAS number is 1435-52-5 and the linear formula is Br2C6H3F.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies 1,4-Dibromo-2-fluorobenzene with an assay of 98%. We do not represent this product as USP, BP, or EP grade.

How should 1,4-Dibromo-2-fluorobenzene be handled safely?

Based on GHS information, 1,4-Dibromo-2-fluorobenzene is a Warning substance. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment includes a dust mask type N95 (US), eyeshields, and gloves. Handle in a well-ventilated area.