1,4-Butanedithiol
1,4-Butanedithiol (CAS: 1191-08-8), with the molecular formula HS(CH2)4SH and a molecular weight of 122.25 g/mol, is an organic sulfur compound. It serves as a valuable building block in chemical synthesis. Its primary applications include functionalising material surfaces for nanoparticle deposition and in the preparation of modified electrodes for electrochemical applications. This thiol is a key intermediate for researchers and industrial chemists.
- IUPAC
- 1,4-Dimercaptobutane,Tetramethylene dimercaptan
- Synonyms
- HS(CH2)4SH1,4-DimercaptobutaneTetramethylene dimercaptan

Surface Functionalization for Nanoparticle Deposition
1,4-Butanedithiol has been utilised to functionalise the surface of multiwalled carbon nanotubes, enabling the precise deposition of gold nanoparticles. This process is crucial for developing advanced nanomaterials with tailored electronic and catalytic properties.
Preparation of Modified Electrodes
The compound is employed in synthesising penicillamine-modified gold nanoparticles that are subsequently immobilised onto gold electrodes. This application is relevant in the development of electrochemical sensors and devices.
Organic Synthesis Intermediate
As a dithiol, 1,4-butanedithiol acts as a versatile building block in organic chemistry. It can participate in various reactions to construct more complex molecules, including heterocycles and polymers, making it a useful reagent for diverse synthetic pathways.
| Molecular weight | 122.25 |
|---|---|
| Linear formula | HS(CH2)4SH |
| Assay | 97% |
| Boiling point | 105-106 °C/30 mmHg(lit.) |
| Density | 1.042 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.529(lit.) |
| Application | 1,4-Butanedithiol was used for the functionalization of surface of multiwalled carbon nanotubes for deposition of gold nanoparticles1. It was also used in the preparation of penicillamine-modified gold nanoparticles immobilized gold electrodes2. |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Transport (UN / ADR) | UN 3334 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1,4-Butanedithiol used for?
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1,4-Butanedithiol is used for the functionalisation of surfaces, such as carbon nanotubes, for nanoparticle deposition, and in the preparation of modified electrodes. It also serves as a building block in organic synthesis.
What is the CAS number and formula for 1,4-Butanedithiol?
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The CAS number for 1,4-Butanedithiol is 1191-08-8, and its linear formula is HS(CH2)4SH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1,4-Butanedithiol with an assay of 97%. This product is typically supplied for research and laboratory use. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade unless explicitly stated.
What are the safety considerations when handling 1,4-Butanedithiol?
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1,4-Butanedithiol is a Warning substance that causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including eyeshields, gloves, and suitable respiratory protection, must be used. Handle in a well-ventilated area.
How is 1,4-Butanedithiol packed and shipped?
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1,4-Butanedithiol is carefully packed according to international shipping regulations for hazardous materials and is available for global export by Tech Serve Solutions.
How can I request a quote or sample for 1,4-Butanedithiol?
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To request a quote or a sample of 1,4-Butanedithiol, please use the contact form on our website or contact our sales department directly.
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