1-(4,6-Dichloro-1,3,5-triazin-2-yl)pyrene
1-(4,6-Dichloro-1,3,5-triazin-2-yl)pyrene (CAS 3224-36-0) is a highly efficient fluorescent probe with a molecular weight of 350.20 g/mol and empirical formula C19H9Cl2N3. It exhibits a large solvatochromic shift, with fluorescence emission varying from 435 nm in n-heptane to 492 nm in acetonitrile, making it adaptable to different solvent polarities. Its fluorescence is excited in the blue spectral range with minimal dependence on its microenvironment.
- IUPAC
- 1-(dichloro-1,3,5-triazinyl)pyrene,4,6-Dichloro-2-(1-pyrenyl)-1,3,5-triazine,PyTC2
- Synonyms
- 4,6-Dichloro-2-(1-pyrenyl)-1,3,5-triazinePyTC21-(4,6-Dichloro-1,3,5-triazin-2-yl)pyrene

Fluorescent Labeling
Utilised as a fluorescent probe due to its high quantum efficiency and stable radiative fluorescence lifetime, enabling its use in various microsurroundings.
Solvent Polarity Sensing
Its fluorescence emission demonstrates a significant solvatochromic shift, directly correlating with solvent polarity, making it useful for polarity measurements.
Biochemical and Reagent Applications
Classified under Biochemicals and Reagents, it serves as a valuable tool in research settings for fluorescence-based assays and studies.
| Molecular weight | 350.20 |
|---|---|
| Empirical formula | C19H9Cl2N3 |
| Assay | ≥85% (HPCE) |
| Solubility | chloroform: soluble |
| Application | 1-(4,6-Dichloro-1,3,5-triazin-2-yl)pyrene is a fluorescent probe with high quantum efficiency, exhibiting single exponential decay kinetics. The radiative fluorescence lifetime is almost constant and independent on molecular surroundings allowing this probe to be utilized in a range of microsurroundings with exciting radiation at a constant wavelength (in the blue spectral range). Its fluorescence emission demonstrates a large solvatochromic shift which changes with solvent polarity. For example, the maximum shifts from 435 nm in low polarity n-heptane to 492 nm in high polarity acetonitrile. This product is only sparingly soluble in water 1. |
| Suitability | suitable for fluorescence |


Hazard statements
- H301Toxic if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H410Very toxic to aquatic life with long-lasting effects
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P273Avoid release to the environment
- P301IF SWALLOWED
- P305IF IN EYES
- P501Dispose of contents and container per local regulations
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1/PG 3 |
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | T,N |
| Risk statements (R) | 25-36/37/38-50/53 |
| Safety statements (S) | 26-45-60-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Product Line | BioReagent |
|---|---|
| Fluorescence | λex 458 nm; λem 497 nm in DMF |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-(4,6-Dichloro-1,3,5-triazin-2-yl)pyrene used for?
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This compound is used as a fluorescent probe with high quantum efficiency, adaptable to various microsurroundings due to a stable fluorescence lifetime. Its large solvatochromic shift allows it to sense solvent polarity, making it valuable for fluorescence studies and as a biochemical reagent.
What are the CAS number and empirical formula for this product?
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The CAS number is 3224-36-0, and the empirical formula is C19H9Cl2N3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with an assay of ≥85% (HPCE). We do not represent this product as USP, BP, EP, or any pharmacopoeia grade.
What are the primary safety concerns and handling requirements?
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This product carries significant hazards including acute toxicity (H301), skin irritation (H315), serious eye irritation (H319), respiratory irritation (H335), and is toxic to aquatic life with long-lasting effects (H410). It requires appropriate personal protective equipment, including eyeshields, faceshields, gloves, and a P2 respirator, and must be handled with extreme caution.
How is 1-(4,6-Dichloro-1,3,5-triazin-2-yl)pyrene packed, shipped, and exported?
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As a specialist global supplier and exporter, Tech Serve Solutions adheres to strict international regulations for the packing, shipping, and exporting of fine chemicals like 1-(4,6-Dichloro-1,3,5-triazin-2-yl)pyrene, ensuring safe and compliant delivery worldwide.
How can I request a sample or a quote?
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To request a sample or a quotation for 1-(4,6-Dichloro-1,3,5-triazin-2-yl)pyrene, please contact our sales team through the website or by phone.
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