1,3-Diphenylisobenzofuran
1,3-Diphenylisobenzofuran (CAS 5471-63-6), with the molecular formula C20H14O and a molecular weight of 270.32 g/mol, is a heterocyclic organic compound. It is primarily utilised as a fluorescent probe for detecting superoxide anion radicals and in studies of molecular structure and photophysical properties. This compound serves as a valuable building block in chemical synthesis.
- IUPAC
- 1,3-Diphenyl-2-benzofuran,2,5-Diphenyl-3,4-benzofuran
- Synonyms
- 1,3-Diphenyl-2-benzofuran2,5-Diphenyl-3,4-benzofuran

Fluorescent Probe for Superoxide Anion Radical Detection
1,3-Diphenylisobenzofuran (DPBF) functions as a fluorescent probe for the detection of superoxide anion radicals (O2−) within membrane lipid layers. Its fluorescence quenching properties are employed to quantify these radicals accurately.
Photophysical Studies and Molecular Structure Analysis
DPBF is used in scientific investigations to determine its single crystal molecular structure and to analyse its solution photophysical properties. This aids in understanding the behaviour and characteristics of this heterocyclic compound.
Quencher in Photoinactivation Studies
The compound has been utilised as a quencher in studies concerning the photoinactivation of specific biological systems, such as hematoporphyrin-containing TA-3 mouse mammary carcinoma cells.
| Molecular weight | 270.32 |
|---|---|
| Empirical formula | C20H14O |
| Assay | 97% |
| Application | 1,3-Diphenylisobenzofuran(DPBF) was used as a fluorescent probe for detection of superoxide anion radical (O2−) inside the membrane lipid layer by DPBF fluorescence quenching method1. 1,3-Diphenylisobenzofuran(DPBF) was used as quencher during the photoinactivation of TA-3 mouse mammary carcinoma cells containing hematoporphyrin2. 1,3-Diphenylisobenzofuran(DPBF) was used to study the single crystal molecular structure and solution photophysical properties of DPBF3. |
| Melting point | 128-130 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1,3-Diphenylisobenzofuran used for?
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1,3-Diphenylisobenzofuran is used as a fluorescent probe for detecting superoxide anion radicals, in studies of molecular structure and photophysical properties, and as a quencher in photoinactivation experiments.
What is the CAS number and formula for 1,3-Diphenylisobenzofuran?
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The CAS number for 1,3-Diphenylisobenzofuran is 5471-63-6, and its empirical formula is C20H14O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1,3-Diphenylisobenzofuran with a minimum assay of 97%. We do not represent this product as meeting USP, BP, or EP pharmacopoeial standards.
What are the safety and handling recommendations for 1,3-Diphenylisobenzofuran?
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Handling 1,3-Diphenylisobenzofuran requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The compound is classified with WGK Germany 3, indicating a high hazard level.
How is 1,3-Diphenylisobenzofuran typically packed and exported?
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As a specialist global supplier, Tech Serve Solutions exports 1,3-Diphenylisobenzofuran. Packaging is designed to ensure product integrity and compliance with international shipping regulations.
How can I request a quote or sample for 1,3-Diphenylisobenzofuran?
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To request a quote or a sample of 1,3-Diphenylisobenzofuran, please contact our sales department via the website or listed contact details.
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