1,3-Diiodo-5,5-dimethylhydantoin
1,3-Diiodo-5,5-dimethylhydantoin (CAS: 2232-12-4) is a halogenated heterocyclic compound with the molecular formula C5H6I2N2O2 and a molecular weight of 379.92 g/mol. It serves as a versatile reagent primarily in chemical synthesis, particularly for iodination reactions. Its applications extend to the preparation of nitriles and the chemoselective iododesilylation of silylated alkenes, contributing to complex organic molecule construction.
- IUPAC
- DIH
- Synonyms
- 2232-12-4C5H6I2N2O2DIH
Efficient Iodination Reagent
DIH is recognised as a highly efficient and economical reagent for various iodination reactions in organic synthesis.
Nitrile Preparation
This compound is employed in the preparation of nitriles from corresponding alcohols and amines through an oxidative conversion process.
Iododesilylation
It is utilised for chemoselective and stereospecific iododesilylation of silylated alkenes, a key transformation in complex molecule synthesis.
Sulfonylamidation Reactions
1,3-Diiodo-5,5-dimethylhydantoin facilitates the preparation of N-benzyl toluenesulfonamides via sulfonylamidation of alkylbenzenes.
| Molecular weight | 379.92 |
|---|---|
| Empirical formula | C5H6I2N2O2 |
| Assay | ≥96% |
| Storage temperature | −20°C |
| Application | DIH - Highly efficient and economical reagent for IodinationUsed for:• Preparation of nitriles from corresponding alcohols and amines via oxidative conversion1• Chemoselective, stereospecific iododesilylation of silylated alkenes2• Preparation of N-benzyl toluenesulfonamides via sulfonylamidation of alkylbenzenes with toluenesulfonamide in presence of diiododimethylhydantoin3• Iodination reactions4 |
Hazard statements
- H272May intensify fire; oxidiser
- H314Causes severe skin burns and eye damage
- H400Very toxic to aquatic life
Precautionary statements
- P220Keep away from clothing and combustible materials
- P273Avoid release to the environment
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | O,C,N |
| Risk statements (R) | 8-35-50/53 |
| Safety statements (S) | 26-36/37/39-45-60-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1,3-Diiodo-5,5-dimethylhydantoin used for?
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1,3-Diiodo-5,5-dimethylhydantoin (DIH) is used as an efficient reagent for iodination reactions, including the preparation of nitriles from alcohols and amines, chemoselective iododesilylation of silylated alkenes, and sulfonylamidation of alkylbenzenes.
What is the CAS number and formula for 1,3-Diiodo-5,5-dimethylhydantoin?
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The CAS number for 1,3-Diiodo-5,5-dimethylhydantoin is 2232-12-4 and its empirical formula is C5H6I2N2O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1,3-Diiodo-5,5-dimethylhydantoin with an assay of ≥96%. This product is supplied for research and laboratory use and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
How should 1,3-Diiodo-5,5-dimethylhydantoin be handled safely?
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1,3-Diiodo-5,5-dimethylhydantoin is a Danger product (GHS03, GHS05, GHS09) that can cause severe skin burns and eye damage and is very toxic to aquatic life with long-lasting effects. Handle with appropriate personal protective equipment including eyeshields, face shields, suitable gloves, and respiratory protection. Store at -20°C.
How is this chemical packed, shipped, and exported?
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Tech Serve Solutions, as a specialist global supplier and exporter, ensures appropriate packaging and handling for 1,3-Diiodo-5,5-dimethylhydantoin in compliance with international shipping regulations.
How can I request a quote or sample?
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To request a quote or sample of 1,3-Diiodo-5,5-dimethylhydantoin, please contact our sales team through the website or directly via email, providing your specific requirements.
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