1,3-Bis(chloromethyl)-1,1,3,3-tetramethyldisilazane
1,3-Bis(chloromethyl)-1,1,3,3-tetramethyldisilazane (CAS: 14579-91-0) is an organosilicon compound with the molecular formula C6H16Cl2N2Si2 and a molecular weight of 230.28 g/mol. This reactive intermediate is primarily utilised as a building block in organic synthesis. Its structure, featuring chloromethyl groups and a disilazane core, makes it valuable for constructing more complex molecules, including heterocycles and macrocyclic ligands.
- Synonyms
- 3,3-tetramethyldisilazane14579-91-0ClCH2Si(CH3)2NHSi(CH3)2CH2Cl
Heterocycle Synthesis
1,3-Bis(chloromethyl)-1,1,3,3-tetramethyldisilazane serves as a precursor in the synthesis of various 6-membered heterocyclic compounds. The reactive chloromethyl groups facilitate cyclisation reactions.
Ligand Development
This disilazane derivative has been employed in the preparation of specialised ligands, such as macrocyclic diamido-diarsine ligands. These are used in coordination chemistry research.
Organic Building Block
As a versatile organic building block, it enables the introduction of specific structural motifs into target molecules within advanced chemical synthesis pathways.
| Molecular weight | 230.28 |
|---|---|
| Linear formula | ClCH2Si(CH3)2NHSi(CH3)2CH2Cl |
| Assay | 95% |
| Boiling point | 204 °C/760 mmHg(lit.) |
| Density | 1.056 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.467(lit.) |
| Vapour density | >1 (vs air) |
| Application | 1,3-Bis(chloromethyl)-1,1,3,3-tetramethyldisilazane has been used in the synthesis of:• 6-membered heterocycles1• macrocyclic diamido-diarsine ligand, [As2N2]Li2(1,4-dioxane) (where As2N2 = PhAs(CH2SiMe2NSiMe2CH2)2AsPh)22 |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 93 °C / 199.4 °F |
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1,3-Bis(chloromethyl)-1,1,3,3-tetramethyldisilazane used for?
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1,3-Bis(chloromethyl)-1,1,3,3-tetramethyldisilazane is used as a building block in organic synthesis, particularly for creating 6-membered heterocycles and macrocyclic ligands.
What are the CAS number and molecular formula for this compound?
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The CAS number is 14579-91-0, and the linear formula is ClCH2Si(CH3)2NHSi(CH3)2CH2Cl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound with a minimum assay of 95%. This product is intended for laboratory and research use; TSS does not represent it as USP, BP, or EP grade.
How should 1,3-Bis(chloromethyl)-1,1,3,3-tetramethyldisilazane be handled safely?
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This compound is classified as a Warning, with hazards including skin irritation (H315), serious eye irritation (H319), and potential respiratory irritation (H335). Appropriate personal protective equipment, such as gloves and eye shields, and adequate ventilation are required. Refer to the Safety Data Sheet for comprehensive handling instructions.
How is this chemical packed and exported?
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Tech Serve Solutions securely packs and exports chemicals globally, adhering to all relevant shipping regulations for hazardous materials like UN 3265, Class 8, Packing Group II.
How can I request a quote or sample?
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To request a quote or a sample, please contact our sales team through the website or by phone, providing the product name and CAS number (14579-91-0).
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