1,3:4,6-Di-O-benzylidene-D-mannitol
1,3:4,6-Di-O-benzylidene-D-mannitol (CAS: 28224-73-9) is a carbohydrate derivative with the molecular formula C20H22O6. This white crystalline solid, weighing 358.39 g/mol, is primarily utilised as a chiral building block in organic synthesis. Its protected mannitol structure makes it a valuable intermediate for constructing complex molecules, particularly in pharmaceutical research and development, and for creating specialised chiral ligands.
- Synonyms
- 28224-73-9C20H22O6
Chiral Building Block in Organic Synthesis
Serves as a stereochemically defined starting material for the synthesis of complex organic molecules. Its protected diol functionalities allow for selective transformations in multi-step synthetic routes.
Precursor for Chiral Ligands and Auxiliaries
Can be chemically modified to generate chiral ligands or auxiliaries employed in asymmetric catalysis. This aids in the stereoselective synthesis of enantiomerically pure compounds.
Intermediate in Pharmaceutical Research
Used in the development of novel pharmaceutical agents where specific stereochemistry is critical for biological activity. Its structure provides a rigid scaffold for medicinal chemistry exploration.
| Molecular weight | 358.39 |
|---|---|
| Empirical formula | C20H22O6 |
| Assay | ≥98.0% (sum of enantiomers, HPLC) |
| Optical activity | [α]20/D −8.4±0.3°, c = 1% in acetone |
| Melting point | 192-195 °C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1,3:4,6-Di-O-benzylidene-D-mannitol used for?
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1,3:4,6-Di-O-benzylidene-D-mannitol (CAS: 28224-73-9) is primarily used as a chiral building block in organic synthesis, a precursor for chiral ligands and auxiliaries, and as an intermediate in pharmaceutical research.
What are the CAS number and molecular formula for this compound?
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The CAS number for 1,3:4,6-Di-O-benzylidene-D-mannitol is 28224-73-9, and its empirical formula (Hill notation) is C20H22O6.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1,3:4,6-Di-O-benzylidene-D-mannitol with an assay of ≥98.0% (sum of enantiomers, HPLC). We do not represent this product as USP, BP, EP, or other pharmacopoeia grades unless explicitly stated.
What are the safety and handling recommendations for 1,3:4,6-Di-O-benzylidene-D-mannitol?
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This compound has a WGK Germany classification of 3, indicating it is hazardous to water. Appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter, should be used during handling to avoid exposure.
How is this chemical packed and exported by TSS?
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Tech Serve Solutions is a global supplier and exporter of fine chemicals, ensuring secure and compliant packaging for international shipment.
How can I request a sample or quote for 1,3:4,6-Di-O-benzylidene-D-mannitol?
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Please contact our sales team via the website to request a sample or a formal quotation for 1,3:4,6-Di-O-benzylidene-D-mannitol.
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