1,2-Dioleoyl-sn-glycero-3-phosphocholine
1,2-Dioleoyl-sn-glycero-3-phosphocholine (CAS 4235-95-4) is a key synthetic phospholipid comprising two oleic acid chains esterified to a glycerol backbone and a phosphocholine head group. With a molecular weight of 786.11, this lyophilized powder serves as a crucial component in cell biology research and lipid studies. It is widely employed in creating liposomes and artificial membranes, facilitating investigations into membrane structure, function, and lipid metabolism.
- IUPAC
- 1,2-Di(cis-9-octadecenoyl)-sn-glycero-3-phosphocholine,3-sn-Phosphatidylcholine, 1,2-dioleoyl,L-α-Phosphatidylcholine, dioleoyl,L-β,γ-Dioleoyl-α-lecithin,DOPC
- Synonyms
- 3-sn-Phosphatidylcholine, 1,2-dioleoyl,L-α-Phosphatidylcholine, dioleoyl,L-β,γ-Dioleoyl-α-lecithin,DOPC

Liposome Formulation
1,2-Dioleoyl-sn-glycero-3-phosphocholine is a fundamental building block for the formation of liposomes and artificial membranes. Its amphipathic nature allows for the creation of stable lipid bilayers essential for drug delivery systems and biomembrane research.
Biomembrane Research
This compound is extensively used to mimic cellular membranes in laboratory settings. Researchers utilise it to study membrane fluidity, protein-lipid interactions, and the biophysical properties of biological membranes.
Lipid Metabolism Studies
As a glycerophospholipid, DOPC is integral to understanding lipid metabolism pathways. It can be used in biochemical assays to investigate enzymes involved in phospholipid synthesis and degradation.
Biochemical Assays
This reagent is valuable for various biochemical assays requiring a defined lipid environment. Its consistent quality makes it suitable for reproducible experimental outcomes in core bioreagent applications.
| Molecular weight | 786.11 |
|---|---|
| Empirical formula | C44H84NO8P |
| Form | lyophilized powder |
| Storage temperature | −20°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1,2-Dioleoyl-sn-glycero-3-phosphocholine used for?
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1,2-Dioleoyl-sn-glycero-3-phosphocholine (DOPC) is primarily used in scientific research for formulating liposomes and artificial membranes, studying biomembrane structure and function, and investigating lipid metabolism pathways.
What is the CAS number and formula for 1,2-Dioleoyl-sn-glycero-3-phosphocholine?
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The CAS number for 1,2-Dioleoyl-sn-glycero-3-phosphocholine is 4235-95-4. Its empirical formula (Hill notation) is C44H84NO8P, and its molecular weight is 786.11.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1,2-Dioleoyl-sn-glycero-3-phosphocholine as a lyophilized powder. The specific assay and grade are available upon request; TSS does not represent this product as USP, BP, or EP grade.
What are the safety and handling recommendations for this product?
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When handling 1,2-Dioleoyl-sn-glycero-3-phosphocholine, it is advised to wear safety equipment including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The product is assigned a WGK Germany classification of 3.
How is this chemical packed, shipped, and exported?
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Tech Serve Solutions professionally packs, ships, and exports chemicals globally, adhering to all relevant regulations. Specific packaging details are provided with orders, and export documentation is managed by our experienced team.
How can I request a sample or a quote for 1,2-Dioleoyl-sn-glycero-3-phosphocholine?
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To request a sample or a quote, please visit the product page on the Tech Serve Solutions website and use the contact form or call our sales department directly. Our team will respond promptly to your inquiry.
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