1,2-Difluoro-4,5-dimethoxybenzene
1,2-Difluoro-4,5-dimethoxybenzene (CAS: 203059-80-7), a fluorinated aromatic ether with the molecular formula C8H8F2O2 and a molecular weight of 174.14 g/mol, serves as a versatile building block in organic synthesis. This compound is characterised by its difluorinated phenyl ring and two methoxy substituents. It is primarily utilised in research and development for the synthesis of more complex organic molecules, particularly in areas requiring specific electronic or steric properties imparted by the fluorine atoms and ether linkages.
- Synonyms
- 203059-80-7F2C6H2(OCH3)2

Organic Synthesis
Utilised as a key intermediate and building block in the synthesis of novel organic compounds. Its difluorinated aromatic structure makes it valuable for introducing specific functionalities into target molecules.
Pharmaceutical Research
Serves as a precursor or intermediate in the development of potential pharmaceutical agents. The incorporation of fluorine atoms can modify the pharmacokinetic and pharmacodynamic properties of drug candidates.
Materials Science
Can be employed in the synthesis of advanced materials where fluorinated aromatic moieties are desired for tuning properties such as thermal stability, solubility, or electronic behaviour.
Agrochemical Development
Acts as a structural motif in the design and synthesis of new agrochemical compounds. Fluorine substitution can influence efficacy and metabolic stability in pesticides and herbicides.
| Molecular weight | 174.14 |
|---|---|
| Linear formula | F2C6H2(OCH3)2 |
| Assay | 90% |
| Density | 1.226 g/mL at 25 °C(lit.) |
| Melting point | 41-43 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | 92 °C / 197.6 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1,2-Difluoro-4,5-dimethoxybenzene used for?
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1,2-Difluoro-4,5-dimethoxybenzene is primarily used as a building block in organic synthesis, particularly in pharmaceutical research, materials science, and agrochemical development, owing to its unique difluorinated aromatic structure.
What is the CAS number and molecular formula?
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The CAS number for 1,2-Difluoro-4,5-dimethoxybenzene is 203059-80-7, and its molecular formula is C8H8F2O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1,2-Difluoro-4,5-dimethoxybenzene with a minimum assay of 90%. This product is intended for research and chemical synthesis purposes and is not supplied as USP, BP, EP, or other pharmacopoeial grades.
What are the primary hazards associated with this chemical?
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This compound is classified with a Warning signal word and has hazard statements H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Appropriate personal protective equipment, including eyeshields, gloves, and a dust mask (N95 type), should be used when handling.
How is 1,2-Difluoro-4,5-dimethoxybenzene packed, shipped, and exported?
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As a specialist global supplier and exporter since 1998, Tech Serve Solutions ensures that 1,2-Difluoro-4,5-dimethoxybenzene is packaged and shipped in compliance with all relevant international regulations for chemical transport.
How can I request a sample or a quote for 1,2-Difluoro-4,5-dimethoxybenzene?
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To request a sample or a quote, please use the contact form on the Tech Serve Solutions website or email our sales department directly, specifying the product name and CAS number (203059-80-7).
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