1-(2-Chloro-6-fluorobenzyl)piperazine
1-(2-Chloro-6-fluorobenzyl)piperazine (CAS 215655-20-2) is a fluorinated heterocyclic compound with a molecular weight of 228.69 g/mol. This chemical serves as a valuable building block in organic synthesis, particularly within the pharmaceutical and agrochemical industries. Its structure, featuring a chlorinated and fluorinated benzyl group attached to a piperazine ring, makes it a versatile intermediate for creating complex molecular architectures.

Pharmaceutical Intermediate
Utilised in the synthesis of active pharmaceutical ingredients (APIs), where its unique structural features can contribute to the biological activity of drug candidates. It is a key component in the development of novel therapeutics.
Agrochemical Development
Employed as a building block in the creation of new pesticides, herbicides, and fungicides. The presence of halogen atoms can influence the efficacy and environmental persistence of agrochemical compounds.
Organic Synthesis
Serves as a versatile reagent in general organic synthesis for introducing the 2-chloro-6-fluorobenzylpiperazine moiety into larger molecules. It is suitable for research and development in various chemical fields.
| Molecular weight | 228.69 |
|---|---|
| Empirical formula | C11H14ClFN2 |
| Assay | 98% |
| Grade | puriss. |
| Density | 1.202 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.5470(lit.) |

Hazard statements
- H319Causes serious eye irritation
Precautionary statements
- P305IF IN EYES
| Protective equipment | Eyeshields, Gloves, half-mask respirator (EU), half-mask respirator (US), multi-purpose combination respirator cartridge (US) |
|---|---|
| Flash point | >110 °C / >230 °F |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-(2-Chloro-6-fluorobenzyl)piperazine used for?
+
This compound is primarily used as a building block in organic synthesis, particularly in the development of pharmaceuticals and agrochemicals.
What is the CAS number and formula for 1-(2-Chloro-6-fluorobenzyl)piperazine?
+
The CAS number is 215655-20-2 and the empirical formula is C11H14ClFN2.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies this chemical with an assay of 98% and a 'puriss.' grade. We do not represent this product as USP, BP, or EP grade.
How should 1-(2-Chloro-6-fluorobenzyl)piperazine be handled safely?
+
This compound is a warning irritant (H319). Handle with appropriate personal protective equipment, including eyeshields and gloves. Ensure adequate ventilation, and use a suitable respirator if necessary. Store in a cool, dry place.
Is 1-(2-Chloro-6-fluorobenzyl)piperazine a controlled substance?
+
Based on the provided data, there is no indication that this compound is a controlled substance.
How is 1-(2-Chloro-6-fluorobenzyl)piperazine packed and shipped?
+
This chemical is typically packed in suitable containers for safe transport and is exported globally by Tech Serve Solutions, adhering to all relevant shipping regulations.
How can I request a sample or quote for 1-(2-Chloro-6-fluorobenzyl)piperazine?
+
To request a sample or a quote, please contact our sales team through the website or by phone, providing your specific requirements and delivery details.
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis