1,2-Bis(diphenylphosphino)ethane monooxide
1,2-Bis(diphenylphosphino)ethane monooxide (CAS: 984-43-0) is an organophosphorus compound with the molecular formula (C6H5)2POCH2CH2P(C6H5)2 and a molecular weight of 414.42 g/mol. It functions as a valuable ligand and reactant in various chemical syntheses. Its applications include catalysis in radical polymerization and asymmetric allylic alkylations, as well as acting as a linker in the development of PET imaging agents and a reactant in Wittig-Horner olefination reactions.
- IUPAC
- [2-(Diphenylphosphino)ethyl]diphenylphosphine oxide
- Synonyms
- [2-(Diphenylphosphino)ethyl]diphenylphosphine oxide
Catalyst in Polymerisation
This compound serves as a catalyst for the radical polymerisation of methacrylates, facilitating controlled polymer chain growth.
Ligand in Asymmetric Synthesis
It acts as a ligand in asymmetric allylic alkylations, promoting enantioselective transformations critical in chiral synthesis.
Hydroformylation Reagent
1,2-Bis(diphenylphosphino)ethane monooxide is employed in the hydroformylation of substrates like dihydromyrcenol and epoxides, adding formyl groups to molecules.
Linker for Imaging Agents
It functions as a linker, influencing the biodistribution properties of Positron Emission Tomography (PET) tumour imaging agents.
Wittig-Horner Olefination
This chemical is a reactant in the Wittig-Horner olefination, a method for converting aldehydes into alkenes.
| Molecular weight | 414.42 |
|---|---|
| Linear formula | (C6H5)2POCH2CH2P(C6H5)2 |
| Assay | 97% |
| Application | Catalyst for • Radical polymerization of methacrylates1• Asymmetric allylic alkylations2• Hydroformylation of dihydromyrcenol3 and epoxides4Linker having an effect on biodistribution of PET tumor imaging agents5Reactant for Wittig-Horner olefination of aldehydes6 |
| Melting point | 195-199 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1,2-Bis(diphenylphosphino)ethane monooxide used for?
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1,2-Bis(diphenylphosphino)ethane monooxide is used as a catalyst for radical polymerization, in asymmetric allylic alkylations, hydroformylation of epoxides and dihydromyrcenol, as a linker for PET imaging agents, and as a reactant in Wittig-Horner olefination.
What is the CAS number and formula for 1,2-Bis(diphenylphosphino)ethane monooxide?
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The CAS number is 984-43-0, and the linear formula is (C6H5)2POCH2CH2P(C6H5)2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1,2-Bis(diphenylphosphino)ethane monooxide with an assay of 97%. This product is supplied for research and development purposes and is not represented as USP, EP, BP, or any other pharmacopoeia grade.
What are the safety and handling considerations for 1,2-Bis(diphenylphosphino)ethane monooxide?
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Handling requires appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. The compound is classified with a WGK Germany rating of 3, indicating it is hazardous to water.
How is 1,2-Bis(diphenylphosphino)ethane monooxide packed and exported?
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Our products, including 1,2-Bis(diphenylphosphino)ethane monooxide, are carefully packed to meet international shipping regulations and are exported globally by Tech Serve Solutions.
How can I request a sample or quote for 1,2-Bis(diphenylphosphino)ethane monooxide?
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To request a sample or a quotation for 1,2-Bis(diphenylphosphino)ethane monooxide, please contact our sales team through the website or by phone.
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