1,2,2,6,6-Pentamethyl-4-piperidinol
1,2,2,6,6-Pentamethyl-4-piperidinol (CAS: 2403-89-6, C10H21NO) is a substituted piperidine derivative with a molecular weight of 171.28 g/mol. This versatile chemical serves as a key building block in organic synthesis. It is particularly utilised in the preparation of advanced materials, including photostable and fluorescent naphthalimides, chemosensors, and spiropyrans, as well as in amine photoredox reactions. Tech Serve Solutions offers this compound with high purity for research and development purposes.
- IUPAC
- 4-Hydroxy-1,2,2,6,6-pentamethylpiperidine,HOPEMP,NSC 364075
- Synonyms
- 4-Hydroxy-1,2,2,6,6-pentamethylpiperidineHOPEMPNSC 3640756,6-Pentamethyl-4-piperidinol

Synthesis of Naphthalimide Derivatives
Acts as a reactant in the synthesis of photostable blue emitting naphthalimides and blue fluorescent naphthalimide pH chemosensors, crucial for advanced optical materials and sensing applications.
Preparation of Crowded Piperidines
Utilised in the synthesis of complex piperidine structures, including those with intramolecularly hydrogen-bonded nitrogen, contributing to the development of novel heterocyclic compounds.
Spiropyran and Spirooxazine Synthesis
Serves as a precursor in the preparation of spiropyrans and spirooxazines, which are classes of compounds known for their photochromic properties.
Amine Photoredox Catalysis
Employed as a reactant in amine photoredox reactions, facilitating modern synthetic methodologies in organic chemistry.
| Molecular weight | 171.28 |
|---|---|
| Empirical formula | C10H21NO |
| Assay | ≥99.0% (GC) |
| Impurities tested | ≤1% water |
| Application | Reactant for: Synthesis of photostable blue emitting naphthalimides1 Synthesis of blue fluorescent naphthalimide pH chemosensors2 Synthesis of crowded piperidines with intramolecularly hydrogen-bonded nitrogen3 Synthesis of spiropyrans and spirooxazines4 Amine photoredox reactions5 |
| Melting point | 72-76 °C |



Hazard statements
- H302Harmful if swallowed
- H314Causes severe skin burns and eye damage
- H317May cause an allergic skin reaction
- H411Toxic to aquatic life with long-lasting effects
Precautionary statements
- P273Avoid release to the environment
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Flash point | 118 °C / 244.4 °F |
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | C,Xn,N |
| Risk statements (R) | 22-34-51/53 |
| Safety statements (S) | 26-36/37/39-45-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1,2,2,6,6-Pentamethyl-4-piperidinol used for?
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1,2,2,6,6-Pentamethyl-4-piperidinol is primarily used as a reactant and building block in organic synthesis, including the preparation of photostable naphthalimides, fluorescent chemosensors, crowded piperidines, and spiropyrans, as well as in amine photoredox reactions.
What is the CAS number and chemical formula for 1,2,2,6,6-Pentamethyl-4-piperidinol?
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The CAS number is 2403-89-6, and the empirical formula is C10H21NO.
What grade and purity does Tech Serve Solutions supply for 1,2,2,6,6-Pentamethyl-4-piperidinol?
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Tech Serve Solutions supplies 1,2,2,6,6-Pentamethyl-4-piperidinol with an assay of ≥99.0% (GC) and ≤1% water. We do not represent this product as USP, BP, or EP grade.
What are the primary safety hazards associated with 1,2,2,6,6-Pentamethyl-4-piperidinol?
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1,2,2,6,6-Pentamethyl-4-piperidinol is classified as dangerous. It is harmful if swallowed (H302), causes severe skin burns and eye damage (H314), may cause an allergic skin reaction (H317), and is toxic to aquatic life with long lasting effects (H411). Appropriate personal protective equipment including a dust mask (N95), eyeshields, face shield, and gloves should be used.
How is 1,2,2,6,6-Pentamethyl-4-piperidinol packed and shipped?
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As a global supplier and exporter, Tech Serve Solutions ensures appropriate packaging for safe handling, storage, and transportation of chemicals like 1,2,2,6,6-Pentamethyl-4-piperidinol in compliance with international regulations.
How can I request a sample or quote for 1,2,2,6,6-Pentamethyl-4-piperidinol?
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To request a sample or quote for 1,2,2,6,6-Pentamethyl-4-piperidinol, please contact our sales department through the website or by phone. Our team will be pleased to assist with your inquiry.
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