1,1-Dimethylpropylmagnesium chloride solution
1,1-Dimethylpropylmagnesium chloride solution (CAS 28276-08-6), with the linear formula C2H5C(CH3)2MgCl and a molecular weight of 130.90 g/mol, is a potent Grignard reagent supplied by Tech Serve Solutions. Typically available as a 1.0 M solution in diethyl ether, this organometallic compound serves as a vital building block in organic synthesis. It is crucial for forming new carbon-carbon bonds in the preparation of complex molecules.
- Synonyms
- tert-Amylmagnesium chloride solutionC2H5C(CH3)2MgCl solution
Organic Synthesis Reagent
As a Grignard reagent, 1,1-Dimethylpropylmagnesium chloride is widely employed for nucleophilic addition to carbonyl compounds, epoxides, and nitriles. It is instrumental in introducing the tert-amyl group into various organic structures.
Pharmaceutical Intermediate Production
This compound facilitates the synthesis of complex organic molecules that can serve as intermediates in the development of active pharmaceutical ingredients (APIs). Its reactivity allows for efficient construction of carbon skeletons.
Fine Chemical Manufacturing
It is used in the manufacture of fine chemicals where precise carbon-carbon bond formation is required. The reagent's ability to react with a range of electrophiles makes it a versatile tool in custom synthesis projects.
| Molecular weight | 130.90 |
|---|---|
| Linear formula | C2H5C(CH3)2MgCl |
| Density | 0.831 g/mL at 25 °C |
| Concentration | 1.0 M in diethyl ether |
Hazard statements
- H225Highly flammable liquid and vapour
- H261In contact with water releases flammable gas
- H302Harmful if swallowed
- H314Causes severe skin burns and eye damage
- H336May cause drowsiness or dizziness
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P231Handle under inert gas
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P422
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | -40 °C / -40 °F |
| Transport (UN / ADR) | UN 3399 4.3/PG 1 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,C |
| Risk statements (R) | 11-14/15-19-22-34-67 |
| Safety statements (S) | 16-26-36/37/39-43-45 |
| Supplemental hazards | May form explosive peroxides., Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1,1-Dimethylpropylmagnesium chloride solution used for?
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1,1-Dimethylpropylmagnesium chloride solution is primarily used as a Grignard reagent in organic synthesis to form new carbon-carbon bonds, particularly in the production of pharmaceutical intermediates and fine chemicals.
What is the CAS number and formula for 1,1-Dimethylpropylmagnesium chloride solution?
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The CAS number is 28276-08-6 and the linear formula is C2H5C(CH3)2MgCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product as a 1.0 M solution in diethyl ether. We do not represent this product as USP, BP, or EP grade.
What are the safety and handling considerations for this product?
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This compound is highly flammable (flash point -40 °C), reacts violently with water, and can form explosive peroxides. It is corrosive and can cause respiratory irritation. Strict adherence to safety protocols, including the use of appropriate personal protective equipment (gloves, goggles, respirator) and working in a well-ventilated area away from ignition sources and water, is essential.
How is 1,1-Dimethylpropylmagnesium chloride solution packed, shipped, and exported?
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As a hazardous material (UN 3399, Class 4.3), it is packed in compliance with international regulations for flammable solids and water-reactive substances. TSS exports this chemical globally, adhering to all necessary shipping and customs requirements.
How can I request a quote or sample?
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To request a quote or a sample, please contact our sales department through the website or by phone, providing your specific requirements and shipping details.
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