1,1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10-Henicosafluoro-12-iodododecane
1,1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10-Henicosafluoro-12-iodododecane (CAS 2043-54-1) is a fluorinated organic compound with the molecular formula CF 3(CF 2)9CH 2CH 2I. This perfluorinated alkyl iodide serves as a valuable building block in fluorous synthesis and specialty chemical applications. Its unique structure allows for the introduction of a long fluorinated chain into various molecules, facilitating separation and purification processes.
- IUPAC
- 1-Iodo-1H,1H,2H,2H-perfluorododecane,1H,1H,2H,2H-Perfluorododecyl iodide
- Synonyms
- 2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10-Henicosafluoro-12-iodododecane1-Iodo-1H,1H,2H,2H-perfluorododecane1H,1H,2H,2H-Perfluorododecyl iodide

Fluorous Synthesis
This compound is extensively used as a precursor or tag in fluorous synthesis. The highly fluorinated segment enables phase separation with fluorous solid-phase extraction (FSPE) techniques, simplifying product isolation and catalyst recovery.
Specialty Chemical Synthesis
It acts as an important intermediate in the synthesis of specialised fluorinated materials and complex organic molecules. The terminal iodide allows for further functionalization via various coupling reactions.
Rf-Tagged Building Blocks
The molecule serves as a key component for creating Rf-tagged building blocks, which are essential for developing advanced materials and pharmaceutical intermediates where fluorinated moieties are desired.
| Molecular weight | 674.03 |
|---|---|
| Linear formula | CF3(CF2)9CH2CH2I |
| Assay | ≥95.0% (GC) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1,1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10-Henicosafluoro-12-iodododecane used for?
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This compound is primarily used as a building block in fluorous synthesis, for creating Rf-tagged molecules, and in specialty chemical synthesis to introduce fluorinated chains.
What are the CAS number and molecular formula for this chemical?
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The CAS number is 2043-54-1, and the molecular formula is CF 3(CF 2)9CH 2CH 2I.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1,1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10-Henicosafluoro-12-iodododecane with an assay of ≥95.0% (GC). TSS does not represent this product as USP, BP, EP, or other pharmacopoeia grades.
How should 1,1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10-Henicosafluoro-12-iodododecane be handled?
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This compound is a skin, eye, and respiratory irritant. Handle with appropriate personal protective equipment, including dust masks (type N95 US recommended), eyeshields, and gloves, in a well-ventilated area. Avoid breathing dust or vapours.
How is this chemical packed and shipped?
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1,1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10-Henicosafluoro-12-iodododecane is carefully packed according to international shipping regulations and is available for export globally by Tech Serve Solutions.
How can I request a sample or obtain a quote?
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To request a sample or obtain a quote for 1,1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10-Henicosafluoro-12-iodododecane, please contact the TSS sales team via our website or direct inquiry.
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