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1-Methylpyrazole-4-boronic acid pinacol ester

1-Methylpyrazole-4-boronic acid pinacol ester chemical structure
CAS Number761446-44-0
FormulaC10H17BN2O2
Mol. Weight208.07 g/mol

What is 1-Methylpyrazole-4-boronic acid pinacol ester?

1-Methylpyrazole-4-boronic acid pinacol ester is a chemical compound with CAS number 761446-44-0 and molecular formula C10H17BN2O2. It is used in various industrial and research applications.

Applications

Reagent used for
• Suzuki-Miyaura cross-coupling reactions1,2,3
• Transesterification reactions4

Reagent used for preparation of
• Aminothiazoles as γ-secretase modulators5
• Amino-pyrido-indol-carboxamides, as potential JAK2 inhibitors for myeloproliferative disorders therapy6
• Pyridine derivatives as TGF-β1 and activin A signalling inhibitors7
• MK-2461 analogs as inhibitors of c-Met kinase for the treatment of cancer8

Specifications

Molecular Weight

208.07 g/mol

Assay/Purity

95%

Safety Information

GHS07GHS07
Signal Word

Warning

Hazard Statements

H302-H315-H319-H335

Precautionary Statements

P261-P305 + P351 + P338

Required PPE

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Melting Point

59-64 °C(lit.)

WGK Germany

3

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