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Vinylboronic acid pinacol ester

Vinylboronic acid pinacol ester chemical structure
CAS Number75927-49-0
FormulaC8H15BO2
Mol. Weight154.01 g/mol

What is Vinylboronic acid pinacol ester?

Vinylboronic acid pinacol ester is a chemical compound with CAS number 75927-49-0 and molecular formula C8H15BO2. It is used in various industrial and research applications.

Applications

Reagent used for
• Suzuki-Miyaura coupling reactions1
• Mizoroki-Heck reactions (cascade reaction)1
• Intramolecular Nozaki-Hiyama-Kishi reactions2
• Stereoselective Cu-catalyzed γ-selective and stereospecific coupling3
• Control of stereoselectivity and mechanistic portrait on intramolecular (4+1)-cycloaddition of dialkoxycarbenes4
• Regio- and stereoselective synthesis of trisubstituted alkenes via gold(I)-catalyzed hydrophosphoryloxylation of haloalkynes followed by Pd-catalyzed consecutive cross-coupling reactions5
• Asymmetric Birch reductive alkylation6

Reagent used in Preparation of
• Molecular tubes for lipid sensing7
• Enzymatic inhibitors, antibiotics, receptor analogs, and other biologically significant compounds (including total syntheses)8,

Specifications

Molecular Weight

154.01 g/mol

Assay/Purity

95%

Density

0.908 g/mL at 25 °C(lit.)

Safety Information

GHS02GHS02
GHS07GHS07
Signal Word

Warning

Hazard Statements

H226-H317

Precautionary Statements

P280

Required PPE

Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter

WGK Germany

3

Frequently Asked Questions