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17-(Allylamino)-17-demethoxygeldanamycin

17-(Allylamino)-17-demethoxygeldanamycin chemical structure
CAS Number75747-14-7
FormulaC31H43N3O8
Mol. Weight585.69 g/mol

What is 17-(Allylamino)-17-demethoxygeldanamycin?

17-(Allylamino)-17-demethoxygeldanamycin is a chemical compound with CAS number 75747-14-7 and molecular formula C31H43N3O8. It is used in various industrial and research applications.

Applications

17-(Allylamino)-17-demethoxygeldanamycin (17-AAG) inhibits heat shock protein 90 (Hsp90), the expression of heat shock factor-1, and the activity of oncogenic proteins such as N-ras, Ki-ras, c-Akt, and p185erB2. In addition to its anti-tumor effects, 17-AAG also induces apoptosis.

Specifications

Molecular Weight

585.69 g/mol

Assay/Purity

≥98% (HPLC)

Solubility

DMSO: soluble
methanol: soluble

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