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4-Hydroxyphenylboronic acid

4-Hydroxyphenylboronic acid chemical structure
CAS Number71597-85-8
FormulaHOC6H4B(OH)2
Mol. Weight137.93 g/mol

What is 4-Hydroxyphenylboronic acid?

4-Hydroxyphenylboronic acid is a chemical compound with CAS number 71597-85-8 and molecular formula HOC6H4B(OH)2. It is used in various industrial and research applications.

Applications

Reagent used for
• Suzuki-Miyaura coupling and Stille coupling and potential for introducing different alkyl groups1
• Palladium-catalyzed aminocarbonylation and cross-coupling reactions2
• Bio-supported palladium nanoparticles as phosphine-free catalyst for Suzuki reaction in water3
• Cu2O-catalyzed aerobic oxidative cross-coupling of tetrazoles4

Reagent used in Preparation of
• PDK1 inhibitory activity (cancer cell growth, survival, and tumorigenesis inhibitor)5
• Rod-like dendronized polymers contg. G4 and G5 ester dendrons via macromonomer approach by living ROMP6
• Estrone-derived cyclopamine analogs as Sonic Hedgehog signaling inhibitors for anti-cancer chemotherapeutics7
• Enzymatic inhibitors for the treatment of gram-negative bacterial infections8

Specifications

Linear Formula

HOC6H4B(OH)2

Molecular Weight

137.93 g/mol

Assay/Purity

≥95.0%

Safety Information

GHS07GHS07
Signal Word

Warning

Hazard Statements

H315-H319-H335

Precautionary Statements

P261-P305 + P351 + P338

Required PPE

dust mask type N95 (US), Eyeshields, Gloves

Melting Point

>230 °C(lit.)

WGK Germany

3

Frequently Asked Questions