4-Hydroxyphenylboronic acid

4-Hydroxyphenylboronic acid
What is 4-Hydroxyphenylboronic acid?
4-Hydroxyphenylboronic acid is a chemical compound with CAS number 71597-85-8 and molecular formula HOC6H4B(OH)2. It is used in various industrial and research applications.
Applications
Reagent used for
• Suzuki-Miyaura coupling and Stille coupling and potential for introducing different alkyl groups1
• Palladium-catalyzed aminocarbonylation and cross-coupling reactions2
• Bio-supported palladium nanoparticles as phosphine-free catalyst for Suzuki reaction in water3
• Cu2O-catalyzed aerobic oxidative cross-coupling of tetrazoles4
Reagent used in Preparation of
• PDK1 inhibitory activity (cancer cell growth, survival, and tumorigenesis inhibitor)5
• Rod-like dendronized polymers contg. G4 and G5 ester dendrons via macromonomer approach by living ROMP6
• Estrone-derived cyclopamine analogs as Sonic Hedgehog signaling inhibitors for anti-cancer chemotherapeutics7
• Enzymatic inhibitors for the treatment of gram-negative bacterial infections8
Specifications
HOC6H4B(OH)2
137.93 g/mol
≥95.0%
Safety Information
GHS07Warning
H315-H319-H335
P261-P305 + P351 + P338
dust mask type N95 (US), Eyeshields, Gloves
>230 °C(lit.)
3
