Applications

N-(Phenylseleno)phthalimide is a versatile selenamide reagent and has been used:
• to selectively derivatize thiols for mass spectrometric analysis¹
• to derivatize thiol peptides in protein digests¹
• in L-prolinamide or pyrrolidine trifluoromethanesulfonamide promoted α-selenenylation reactions of aldehydes and ketones²
• for introducing PhSe into protected glycals³, ketones⁴, aldehydes⁴, stannanes⁵ and exocyclic alkenes⁶