Trifluorothymidine
CAS Number70-00-8
FormulaC10H11F3N2O5
Mol. Weight296.20 g/mol
Trifluorothymidine
What is Trifluorothymidine?
Trifluorothymidine is a chemical compound with CAS number 70-00-8 and molecular formula C10H11F3N2O5. It is used in various industrial and research applications.
Applications
Trifluorothymidine (Trifluridine, TFT) is a substrate used to study the specificity and kinetics of thymidine kinase(s). TFT after phosphorylation may be incorporated into DNA where is induces DNA-damage, consequently TFT is useful for studies of DNA repair mechanisms. TFT may also be used to study mechanisms of inhibition of thymidylate synthase(s).
Specifications
Molecular Weight
296.20 g/mol
Assay/Purity
≥99% (HPLC)
Safety Information
GHS07
GHS08Signal Word
Warning
Hazard Statements
H302-H312-H332-H351
Precautionary Statements
P280
Required PPE
dust mask type N95 (US), Eyeshields, Gloves
Melting Point
190-193 °C(lit.)
EC Number
200-722-8
WGK Germany
3