Diethyl methylphosphonate

Diethyl methylphosphonate
What is Diethyl methylphosphonate?
Diethyl methylphosphonate is a chemical compound with CAS number 683-08-9 and molecular formula CH3P(O)(OC2H5)2. It is used in various industrial and research applications.
Applications
Reactant for the synthesis of:
• Fluoroalkyl α- and β-aminophosphonates1
• Acyclic nucleoside phosphonates with branched phosphonoethoxy-Et chains as potential antivirals2
• Difluoromethyl arylphosphonates3
• Pyridone alkaloids with neuritogenic activity4
• Lipophilic meropenem-derived prodrugs5
• Phomactin cyclohexane core and diterpenoid framework6
• Phosphonylated peptides via solid-phase synthesis7
Specifications
CH3P(O)(OC2H5)2
152.13 g/mol
≥97.0% (GC)
194 °C(lit.)
1.041 g/mL at 25 °C(lit.)
Safety Information
GHS07Warning
H315-H319-H335
P261-P305 + P351 + P338
Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
211-667-4
3
