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2-Methoxyethyl chloroformate

2-Methoxyethyl chloroformate chemical structure
CAS Number628-12-6
FormulaN/A
Mol. Weight138.55 g/mol

What is 2-Methoxyethyl chloroformate?

2-Methoxyethyl chloroformate is a chemical compound with CAS number 628-12-6. It is used in various industrial and research applications.

Applications

Reactant for:
• Preparation of N-bridged bicyclic sulfonamides as inhibitors of γ-secretase1
• Preparation of dimethoxyethyl azodicarboxylate via amidation/oxidation and application to Mitsunobu reaction2
• Regioselective, stereoselective, and kinetically-controlled nickel-catalyzed cyanoesterification of allenes chloroformates and TMSCN3
• Preparation of amino carboxamidobenzothiazoles as Lck inhibitors4
• Preparation of nonracemic spirooxindoles using a stereoselective three-component coupling reaction as the key step and using acylation reactions to add structural diversity5

Specifications

Linear Formula

CH3OCH2CH2OCOCl

Molecular Weight

138.55 g/mol

Boiling Point

157-158 °C(lit.)

Density

1.192 g/mL at 25 °C(lit.)

Safety Information

GHS02GHS02
GHS05GHS05
Signal Word

Danger

Hazard Statements

H226-H314

Precautionary Statements

P280-P305 + P351 + P338-P310

Required PPE

Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter

EC Number

211-026-9

WGK Germany

3

Frequently Asked Questions