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tert-Butyl P,P-dimethylphosphonoacetate

tert-Butyl P,P-dimethylphosphonoacetate chemical structure
CAS Number62327-21-3
FormulaN/A
Mol. Weight224.19 g/mol

What is tert-Butyl P,P-dimethylphosphonoacetate?

tert-Butyl P,P-dimethylphosphonoacetate is a chemical compound with CAS number 62327-21-3. It is used in various industrial and research applications.

Applications

Reactant for:
• Preparation of phosphonate terminated PPH dendrimers as anti-HIV-1 agents1
• Preparation of monodehydro diketopiperazines from ketoacyl amino acid amides via acid-catalyzed cyclization2
• Preparation of α,β-unsaturated esters for use in the guanidine-catalyzed oxa-Michael addition3
• Preparation of myxopyronin B and desmethyl myxopyronin B analogs, with antibacterial activity and inhibitory activity against bacterial RNA polymerase4
• Allylation and subsequent ring-closing metathesis in presence of Grubbs′ catalyst or intramolecular rhodium-catalyzed cyclopropanation reactions5

Specifications

Linear Formula

(CH3O)2P(O)CH2COOC(CH3)3

Molecular Weight

224.19 g/mol

Assay/Purity

≥97.0% (GC)

Boiling Point

86-87 °C/0.02 mmHg(lit.)

Density

1.131 g/mL at 20 °C(lit.)

Safety Information

GHS07GHS07
Signal Word

Warning

Hazard Statements

H315-H319-H335

Precautionary Statements

P261-P305 + P351 + P338

Required PPE

Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter

WGK Germany

3

Frequently Asked Questions

Alternative Names & Synonyms

(CH3O)2P(O)CH2COOC(CH3)3