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5-Nitroindole

5-Nitroindole chemical structure
CAS Number6146-52-7
FormulaC8H6N2O2
Mol. Weight162.15 g/mol

What is 5-Nitroindole?

5-Nitroindole is a chemical compound with CAS number 6146-52-7 and molecular formula C8H6N2O2. It is used in various industrial and research applications.

Applications

Reactant for preparation of:
• Pharmaceutically active 2-oxo-1-pyrrolidine analogues1
• Tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles as potential anticancer immunomodulators2
• Protein Kinase Inhibitors and antiproliferative agents3
• Positive Allosteric Modulators of Metabotropic Glutamate Receptor 4 (mGlu4)4
• Antifungal agents5
• Cannabinoid receptor type 1 (CB1) antagonists6
• Potential anticancer agents7
• Potential antivascular agents8
• Selective Anti-leukemic agents9
• Anti human immunodeficiency virus subtype 1 (HIV-1) agents10

Specifications

Molecular Weight

162.15 g/mol

Assay/Purity

98%

Safety Information

GHS05GHS05
GHS07GHS07
Signal Word

Danger

Hazard Statements

H302-H318

Precautionary Statements

P280-P305 + P351 + P338

Required PPE

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Melting Point

140-142 °C(lit.)

EC Number

228-153-0

WGK Germany

3

Frequently Asked Questions