5-Nitroindole

5-Nitroindole
What is 5-Nitroindole?
5-Nitroindole is a chemical compound with CAS number 6146-52-7 and molecular formula C8H6N2O2. It is used in various industrial and research applications.
Applications
Reactant for preparation of:
• Pharmaceutically active 2-oxo-1-pyrrolidine analogues1
• Tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles as potential anticancer immunomodulators2
• Protein Kinase Inhibitors and antiproliferative agents3
• Positive Allosteric Modulators of Metabotropic Glutamate Receptor 4 (mGlu4)4
• Antifungal agents5
• Cannabinoid receptor type 1 (CB1) antagonists6
• Potential anticancer agents7
• Potential antivascular agents8
• Selective Anti-leukemic agents9
• Anti human immunodeficiency virus subtype 1 (HIV-1) agents10
Specifications
162.15 g/mol
98%
Safety Information
GHS05
GHS07Danger
H302-H318
P280-P305 + P351 + P338
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
140-142 °C(lit.)
228-153-0
3
