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Trimethyl phosphonoacetate

Trimethyl phosphonoacetate chemical structure
CAS Number5927-18-4
FormulaN/A
Mol. Weight182.11 g/mol

What is Trimethyl phosphonoacetate?

Trimethyl phosphonoacetate is a chemical compound with CAS number 5927-18-4. It is used in various industrial and research applications.

Applications

Reactant involved in:
• Intramolecular Mannich-type reactions to produce the sarain A diazatricyclic core1
• Organocatalytic oxa-Michael reactions2
• Prenylation and geranylation of oxindoles3
• Intramolecular Horner-Wadsworth-Emmons reactions4,5
• Olefin cross-metathesis / heterocyclization6

Specifications

Linear Formula

(CH3O)2P(O)CH2CO2CH3

Molecular Weight

182.11 g/mol

Assay/Purity

≥98.0% (GC)

Boiling Point

118 °C/0.85 mmHg(lit.)
265-268 °C(lit.)

Density

1.125 g/mL at 25 °C(lit.)

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