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3-Maleimidobenzoic acid N-hydroxysuccinimide ester

3-Maleimidobenzoic acid N-hydroxysuccinimide ester chemical structure
CAS Number58626-38-3
FormulaC15H10N2O6
Mol. Weight314.25 g/mol

What is 3-Maleimidobenzoic acid N-hydroxysuccinimide ester?

3-Maleimidobenzoic acid N-hydroxysuccinimide ester is a chemical compound with CAS number 58626-38-3 and molecular formula C15H10N2O6. It is used in various industrial and research applications.

Applications

Heterobifunctional crosslinking reagent reactive toward primary amine and sulfhydryl. Typically, coupled initially to molecules containing primary amines by amide bonds buffered at pH 7.0, followed by coupling to compounds containing sulfhydryl by thioether at same pH. Useful for preparation of enzyme immunoconjugates and hapten carrier molecule conjugates.

Specifications

Molecular Weight

314.25 g/mol

Solubility

ethyl acetate or DMF: ≤20 mg/mL (may require addition of solvent to coupling buffer to at least 5% to maintain solubility)

Safety Information

GHS07GHS07
Signal Word

Warning

Hazard Statements

H315-H319-H335

Precautionary Statements

P261-P305 + P351 + P338

Melting Point

175-177 °C(lit.)

WGK Germany

3

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