3-Maleimidobenzoic acid N-hydroxysuccinimide ester

CAS Number58626-38-3
FormulaC15H10N2O6
Mol. Weight314.25 g/mol
3-Maleimidobenzoic acid N-hydroxysuccinimide ester
What is 3-Maleimidobenzoic acid N-hydroxysuccinimide ester?
3-Maleimidobenzoic acid N-hydroxysuccinimide ester is a chemical compound with CAS number 58626-38-3 and molecular formula C15H10N2O6. It is used in various industrial and research applications.
Applications
Heterobifunctional crosslinking reagent reactive toward primary amine and sulfhydryl. Typically, coupled initially to molecules containing primary amines by amide bonds buffered at pH 7.0, followed by coupling to compounds containing sulfhydryl by thioether at same pH. Useful for preparation of enzyme immunoconjugates and hapten carrier molecule conjugates.
Specifications
Molecular Weight
314.25 g/mol
Solubility
ethyl acetate or DMF: ≤20 mg/mL (may require addition of solvent to coupling buffer to at least 5% to maintain solubility)
Safety Information
GHS07Signal Word
Warning
Hazard Statements
H315-H319-H335
Precautionary Statements
P261-P305 + P351 + P338
Melting Point
175-177 °C(lit.)
WGK Germany
3
