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p-Tolylboronic acid

p-Tolylboronic acid chemical structure
CAS Number5720-05-8
FormulaCH3C6H4B(OH)2
Mol. Weight135.96 g/mol

What is p-Tolylboronic acid?

p-Tolylboronic acid is a chemical compound with CAS number 5720-05-8 and molecular formula CH3C6H4B(OH)2. It is used in various industrial and research applications.

Applications

Reagent used for
• Palladium (Pd)-catalyzed direct arylation1
• Direct Palladium(II)-Catalyzed Synthesis2
• Palladium-catalyzed arylation by Suzuki-Miyaura cross-coupling in water3
• Cyclopalladation4
• Tandem-type Pd(II)-catalyzed oxidative Heck reaction and intramolecular C-H amidation sequence5
• Ruthenium catalyzed direct arylation6
• Rhodium-catalyzed asymmetric conjugate addition7
• Ligand-free copper-catalyzed cross-coupling reactions8
• Regioselective arylation and alkynylation by Suzuki-Miyaura and Sonogashira cross-coupling reactions9
• Ligand-free Suzuki, Sonogashira, and Heck cross-coupling reactions10

Reagent used in Preparation of
• Catalysts for Suzuki-Miyaura cross-coupling of aryl bromides4

Specifications

Linear Formula

CH3C6H4B(OH)2

Molecular Weight

135.96 g/mol

Assay/Purity

97%

Safety Information

GHS07GHS07
Signal Word

Warning

Hazard Statements

H315-H319-H335

Precautionary Statements

P261-P305 + P351 + P338

Required PPE

dust mask type N95 (US), Eyeshields, Gloves

Melting Point

256-263 °C(lit.)

WGK Germany

3

Frequently Asked Questions