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AP-18

AP-18 chemical structure
CAS Number55224-94-7
FormulaN/A
Mol. Weight209.67 g/mol

What is AP-18?

AP-18 is a chemical compound with CAS number 55224-94-7. It is used in various industrial and research applications.

Applications

AP-18 is a selective TRPA1 channel blocker. AP-18 blocks the transient receptor potential ankyrin 1 receptors and can reduce chronic pain associated with arthritis. AP-18 reduces cinnamaldehyde-induced nociception in vivo and blocks cold- and mustard oil-induced activation of mouse TRPA1 but not capsaicin-induced activation. AP-18 reverses CFA-induced mechanical hyperalgesia in mice

Specifications

Molecular Weight

209.67 g/mol

Assay/Purity

≥98% (HPLC)

Solubility

DMSO: >10 mg/mL

Safety Information

GHS07GHS07
Signal Word

Warning

Hazard Statements

H302

Required PPE

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

WGK Germany

3

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