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3-Cyanoindole

3-Cyanoindole chemical structure
CAS Number5457-28-3
FormulaC9H6N2
Mol. Weight142.16 g/mol

What is 3-Cyanoindole?

3-Cyanoindole is a chemical compound with CAS number 5457-28-3 and molecular formula C9H6N2. It is used in various industrial and research applications.

Applications

Reactant for preparation of:
• Tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles as potential anticancer immunomodulators1
• Inhibitors of the C-terminal domain of RNA polymerase II with antitumor activities
• 4-substituted β-lactams2
• Biologically active Indoles3
• Inhibitors of glycogen synthase kinase 3β (GSK-3)4
• HIV-1 integrase inhibitors5
• Indole fragments as inosine monophosphate dehydrogenase (IMPDH) inhibitors6
• Aziridinomitosene skeleton7
• Potential antiviral agents8

Reactant for:
• Intramolecular oxidative C-H coupling reactions with applications in medium-ring synthesis techniques9

Specifications

Molecular Weight

142.16 g/mol

Assay/Purity

98%

Safety Information

GHS07GHS07
Signal Word

Warning

Hazard Statements

H302-H312-H315-H319-H332-H335

Precautionary Statements

P261-P280-P305 + P351 + P338

Required PPE

dust mask type N95 (US), Eyeshields, Gloves

Melting Point

179-182 °C(lit.)

WGK Germany

3

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