4-Aminoindole

4-Aminoindole
What is 4-Aminoindole?
4-Aminoindole is a chemical compound with CAS number 5192-23-4 and molecular formula C8H8N2. It is used in various industrial and research applications.
Applications
Reactant for preparation of:
• Inhibitors of bacterial thymidylate synthase1
• Mimetics of non-alkaloid toxin lignan anticancer and antiviral agent Podophyllotoxin (PPT)2
• Inhibitors of Gli1-mediated transcription in the Hedgehog pathway3
• Protein kinase C θ (PKCθ) inhibitors4
• Indolic non-peptidic HIV protease inhibitors5
• Transient receptor potential cation channel subfamily V member 1 (TRPV1) antagonists6
• Cyclooxygenase-2 (COX-2) and lipoxygenase (LOX) inhibitors7
• 11β-hydroxysteroid dehydrogenase 1 (11β-HSD1) inhibitors8
• Short chain 4-substituted indoles as potent αvβ3 antagonist9
• Ligands of serotonin transporter and 5-HT1A receptors10
Specifications
132.16 g/mol
97%
Safety Information
GHS07Warning
H315-H319-H335
P261-P305 + P351 + P338
dust mask type N95 (US), Eyeshields, Gloves
106-109 °C(lit.)
3
