5-Aminoindole
CAS Number5192-03-0
FormulaC8H8N2
Mol. Weight132.16 g/mol
5-Aminoindole
What is 5-Aminoindole?
5-Aminoindole is a chemical compound with CAS number 5192-03-0 and molecular formula C8H8N2. It is used in various industrial and research applications.
Applications
Reactant for preparation of:
• Smac mimetics that bind to the BIR2 domain of the anti-apoptotic protein XIAP1
• Cytotoxic and antimitotic agents2
• Insulin-like growth factor 1 receptor inhibitors3
• Antitumoral agents4
• Factor Xa inhibitor5
• Potential antivascular agents6
• Gli1-mediated transcription in the Hedgehog pathway7
• Inhibitors of receptor tyrosine kinase with antiangiogenic effects8
• PKCθ inhibitors9
• HIV protease inhibitors10
Specifications
Molecular Weight
132.16 g/mol
Assay/Purity
97%
Safety Information
GHS07Signal Word
Warning
Hazard Statements
H302-H315-H319-H335
Precautionary Statements
P261-P305 + P351 + P338
Required PPE
dust mask type N95 (US), Eyeshields, Gloves
Melting Point
131-133 °C (dec.)(lit.)
EC Number
225-977-2
WGK Germany
3