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Terfenadine

Terfenadine chemical structure
CAS Number50679-08-8
FormulaC32H41NO2
Mol. Weight471.67 g/mol

What is Terfenadine?

Terfenadine is a chemical compound with CAS number 50679-08-8 and molecular formula C32H41NO2. It is used in various industrial and research applications.

Applications

Terfenadine has been used to study the role of histamine in itch related to proteinase-activated receptors (PARs) in mice1. Terfenadine has also been used to block histamine receptor type 1 to study the pathogenesis of 2,4-dinitrobenzene sulfonic acid (DNBS)-induced ulcerative colitis in rats2.

Specifications

Molecular Weight

471.67 g/mol

Solubility

chloroform: soluble250 mg plus 5 ml of solvent, clear to very slightly hazy, colorless to faintly yellow
H2O: soluble0.01 mg/mL at 30 °C
1 M HCl: soluble0.12  mg/mL at 30 °C
hexane: soluble0.34  mg/mL at 30 °C
0.1 M tartaric acid: soluble0.45  mg/mL
0.1 M citric acid: soluble1.1  mg/mL
methanol: soluble37.5  mg/mL at 30 °C
ethanol: soluble in salt form37.8  mg/mL at 30 °C

Safety Information

Hazard Statements

H413

EC Number

256-710-8

WGK Germany

2

Frequently Asked Questions