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Actinomycin D

Actinomycin D chemical structure
CAS Number50-76-0
FormulaC62H86N12O16
Mol. Weight1255.42 g/mol

What is Actinomycin D?

Actinomycin D is a chemical compound with CAS number 50-76-0 and molecular formula C62H86N12O16. It is used in various industrial and research applications.

Applications

Actinomycin D is an antineoplastic antibiotic that inhibits cell proliferation with wide-ranging applications ranging from a selection agent in cell culture, use in studies of suppressing HIV-replication and programmed cell death of PC12 cells, and as an antibiotic in treatment of various malignant neoplasms, including Wilm′s tumour and the sarcomas. Recommended for us in cell culture applications at 1μg/mL.

Specifications

Molecular Weight

1255.42 g/mol

Assay/Purity

≥95%

Solubility

ethanol, DMSO: soluble (Stable in aqueous solutions at 2-8 °C.)

Safety Information

GHS06GHS06
Signal Word

Danger

Hazard Statements

H300

Precautionary Statements

P264-P301 + P310

Required PPE

Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges

Melting Point

251-253

EC Number

200-063-6

WGK Germany

3

Frequently Asked Questions