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4-Chloro-2-methylthiopyrimidine

4-Chloro-2-methylthiopyrimidine chemical structure
CAS Number49844-90-8
FormulaC5H5ClN2S
Mol. Weight160.62 g/mol

What is 4-Chloro-2-methylthiopyrimidine?

4-Chloro-2-methylthiopyrimidine is a chemical compound with CAS number 49844-90-8 and molecular formula C5H5ClN2S. It is used in various industrial and research applications.

Applications

4-Chloro-2-methylthiopyrimidine was used in the total synthesis of the marine alkaloid variolin B1 and 2-hydroxy-4-pyrimidinecarboxylic acid1. It was used in the synthesis of 2,4-disubstituted pyrimidines, a novel class of KDR kinase inhibitors2. It was used as building block in medicinal chemistry synthesis.3,4

Specifications

Molecular Weight

160.62 g/mol

Assay/Purity

98%

Boiling Point

139-140 °C/36 mmHg(lit.)

Density

1.381 g/mL at 25 °C(lit.)

Safety Information

GHS05GHS05
Signal Word

Danger

Hazard Statements

H314

Precautionary Statements

P280-P305 + P351 + P338-P310

Required PPE

Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter

Melting Point

−2 °C(lit.)

EC Number

256-500-6

WGK Germany

3

Frequently Asked Questions