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2(5H)-Furanone

2(5H)-Furanone chemical structure
CAS Number497-23-4
FormulaC4H4O2
Mol. Weight84.07 g/mol

What is 2(5H)-Furanone?

2(5H)-Furanone is a chemical compound with CAS number 497-23-4 and molecular formula C4H4O2. It is used in various industrial and research applications.

Applications

2(5H)-Furanone (γ-Crotonolactone) has been used in:
• synthesis of (+)-L-733,060, (+)-CP-99,994 and (2S,3R)-3-hydroxypipecolic acid1
• synthesis of 5-substituted 2(5H) furanones (γ-butenolides) via direct aldol reaction with aromatic aldehydes catalyzed by bifunctional aminothiourea and aminosquaramide organocatalysts2
• Michael addition reactions3 for synthesis of lignans4
• three-component Michael-Aldol reactions with an aldehyde anda thiolate5 or carbanion6

Specifications

Molecular Weight

84.07 g/mol

Assay/Purity

98%

Boiling Point

86-87 °C/12 mmHg(lit.)

Density

1.185 g/mL at 25 °C(lit.)

Safety Information

GHS07GHS07
Signal Word

Warning

Hazard Statements

H315-H319-H335

Precautionary Statements

P261-P305 + P351 + P338

Required PPE

Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter

Melting Point

4-5 °C(lit.)

EC Number

207-839-3

WGK Germany

3

Frequently Asked Questions