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Tetrodotoxin

Tetrodotoxin chemical structure
CAS Number4368-28-9
FormulaC11H17N3O8
Mol. Weight319.27 g/mol

What is Tetrodotoxin?

Tetrodotoxin is a chemical compound with CAS number 4368-28-9 and molecular formula C11H17N3O8. It is used in various industrial and research applications.

Applications

Tetrodotoxin has been used as standard during HPLC-based analysis of biotoxins from P. punctata tentacles whole crude extract (PHY-N)1. Tetrodotoxin has also been used to study its effects on low-threshold transient (LTT) Ca2+ currents in rat hippocampal interneurons2.

Specifications

Molecular Weight

319.27 g/mol

Assay/Purity

≥98% (HPLC)

Solubility

dilute citrate or acetate buffer: soluble1 mg/mL (dissolve at pH 4-5. Aqueous solutions, pH 4-5, are stable if stored frozen.)
strong acid or alkaline solutions: unstable (destroyed by boiling at pH 2.)

Safety Information

GHS06GHS06
Signal Word

Danger

Hazard Statements

H300 +H310 + H330

Precautionary Statements

P260-P264-P280-P284-P301 + P310-P302 + P350

Required PPE

Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges

EC Number

224-458-8

WGK Germany

3

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