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Dacarbazine

Dacarbazine chemical structure
CAS Number4342-03-4
FormulaC6H10N6O
Mol. Weight182.18 g/mol

What is Dacarbazine?

Dacarbazine is a chemical compound with CAS number 4342-03-4 and molecular formula C6H10N6O. It is used in various industrial and research applications.

Applications

Dacarbazine is a triazine antineoplastic agent that is used for DNA methylation via formation of methyl adducts. It is used to treat metastatic malignant melanomas and Hodgkin′s when used in combination with other antineoplastic agents. It is used to induce apoptosis in human cells1. It has been used to induce hepatotoxicity in mice2.

Specifications

Molecular Weight

182.18 g/mol

Safety Information

GHS07GHS07
GHS08GHS08
Signal Word

Danger

Hazard Statements

H302 + H312 + H332-H315-H319-H335-H340-H350

Precautionary Statements

P201-P261-P280-P305 + P351 + P338-P308 + P313

Required PPE

Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges

EC Number

224-396-1

WGK Germany

3

Frequently Asked Questions