Applications

2,2,3,3,3-Pentafluoro-1-propanol has been used:
• as derivatization reagent in detection of unlabeled and ¹⁵N₂ -labeled L-tryptophan, L-kynurenine, serotonin and quinolinic acid in human and rat plasma by GC-MS¹
• as derivatization reagent in simultaneous analysis of cocaine, cocaethylene and their possible metabolic and pyrolytic products in blood, urine and muscle by GC-MS²
• preparation of trifluoromethyl ynamines which, in turn, converted aldehydes to α-trifluoromethyl-α,β-unsaturated amides³
• to generate fluorinated α-keto ethers with alkenes⁴ and has wide applications in the expanding fluorous research area⁴