Applications

Reactant for:
• Copper-catalyzed cycloaddition reactions¹
• Preparation of orally bioavailable diamide prodrugs that lower glucose in diabetic animals through inhibition of fructose-1,6-bisphosphatase²
• Synthesis of sterol analogs as antifungal agents against plant pathogens³
• Asymmetric synthesis of steroidal 2,5-diketopiperazines prepared via isocyanide chemistry based on stereoselective Ugi four component condensation and subsequent cyclocondensation reactions⁴
• The Passerini reaction⁵