CHEMISTRY8LIFE SCIENCE5MATERIALS SCIENCE4
CHEMISTRY
Products
CHEMISTRY8LIFE SCIENCE5MATERIALS SCIENCE4View All Products
AboutSafetyClientsContacts

p-Toluenesulfonyl isocyanate

p-Toluenesulfonyl isocyanate chemical structure
CAS Number4083-64-1
FormulaCH3C6H4SO2NCO
Mol. Weight197.21 g/mol

What is p-Toluenesulfonyl isocyanate?

p-Toluenesulfonyl isocyanate is a chemical compound with CAS number 4083-64-1 and molecular formula CH3C6H4SO2NCO. It is used in various industrial and research applications.

Applications

p-Toluenesulfonyl isocyanate has been used as :
• derivatization reagent in determination of 3-α-hydroxy tibolone in human plasma by LC-MS/MS1
• derivatization reagent in simultaneous quantitative analysis of diethylene glycol and propylene glycol in pharmaceutical products by HPLC2
• as reagent in the preparation of acetylated syn-1,2-diols3, oxazolidin-2-ones4, 2,3-diamino acids5 and N-tosylcarbonamides6

Specifications

Linear Formula

CH3C6H4SO2NCO

Molecular Weight

197.21 g/mol

Assay/Purity

96%

Boiling Point

144 °C/10 mmHg(lit.)
275-278 °C(lit.)

Density

1.291 g/mL at 25 °C(lit.)

Safety Information

GHS07GHS07
GHS08GHS08
Signal Word

Danger

Hazard Statements

H315-H319-H334-H335

Precautionary Statements

P261-P305 + P351 + P338-P342 + P311

Required PPE

Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter

EC Number

223-810-8

WGK Germany

1

Frequently Asked Questions