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JC-1

JC-1 chemical structure
CAS Number3520-43-2
FormulaC25H27Cl4IN4
Mol. Weight652.23 g/mol

What is JC-1?

JC-1 is a chemical compound with CAS number 3520-43-2 and molecular formula C25H27Cl4IN4. It is used in various industrial and research applications.

Applications

A dual-emission potential-sensitive probe that can be used to measure mitochondrial membrane potential. JC-1 is a green-fluorescent (λex 520 nm) monomer at low membrane potential. At higher potentials, JC-1 forms red-fluorescent (λem 596 nm ) \"J-aggregates,\" which exhibit broad excitation and very narrow emission spectra. The ratio of red to green fluorescence of JC-1 is dependent only on membrane potential, and not influenced by mitochondrial size, shape, or density.

Specifications

Molecular Weight

652.23 g/mol

Assay/Purity

≥90% (HPCE)

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