DL-Dithiothreitol
DL-Dithiothreitol
What is DL-Dithiothreitol?
DL-Dithiothreitol is a chemical compound with CAS number 3483-12-3. It is used in various industrial and research applications.
Applications
An excellent reagent for maintaining SH groups in reduced state; quantitatively reduces disulfides. DTT is effective in sample buffers for reducing protein disulfide bonds prior to SDS-PAGE. DTT can also be used for reducing the disulfide bridge of the cross-linker N,N′-bis(acryloyl)cystami
Specifications
HSCH2CH(OH)CH(OH)CH2SH
154.25 g/mol
for molecular biology
≥99.0% (RT)
≤0.3% 4,5-dihydroxy-1,2-dithiane
1.04 g/mL at 20 °C<br/>1.035 g/mL at 25 °C
H2O: soluble50 mg/mL, clear, colorless
H2O: freely soluble
acetone: freely soluble
chloroform: freely soluble
diethyl ether: freely soluble
ethanol: freely soluble
ethyl acetate: freely soluble
Safety Information
GHS07Warning
H302-H315-H319-H335
P261-P305 + P351 + P338
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
41-44 °C(lit.)
42-43 °C
sulfate (SO42-): ≤50 mg/kg
Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤50 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Na: ≤200 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Zn: ≤5 mg/kg
222-468-7
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