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3,4-Dichlorophenylacetonitrile

3,4-Dichlorophenylacetonitrile chemical structure
CAS Number3218-49-3
FormulaN/A
Mol. Weight186.04 g/mol

What is 3,4-Dichlorophenylacetonitrile?

3,4-Dichlorophenylacetonitrile is a chemical compound with CAS number 3218-49-3. It is used in various industrial and research applications.

Applications

3,4-Dichlorophenylacetonitrile was used in the synthesis of:
• SR 48968, a potent, competitive and selective non-peptide antagonist of the neurokinin A (NK2) receptor1
• tachykinin NK3 receptor antagonist SR 142801, (R)-N-[ 1-[3-[ 1-benzoyl-3-(3,4-dichlororphenyl)-3-piperidinyl]propyyl]-4-phenyl-4-piperidinyl-N-methyl acetamide2
• MDL 105,212, a non-peptide tachykinin receptor antagonist3

Specifications

Linear Formula

Cl2C6H3CH2CN

Molecular Weight

186.04 g/mol

Assay/Purity

98%

Boiling Point

170 °C/12 mmHg(lit.)

Safety Information

GHS07GHS07
Signal Word

Warning

Hazard Statements

H302-H312-H315-H319-H332-H335

Precautionary Statements

P261-P280-P305 + P351 + P338

Required PPE

dust mask type N95 (US), Eyeshields, Gloves

Melting Point

39-42 °C(lit.)

EC Number

221-743-9

WGK Germany

3

Frequently Asked Questions

Alternative Names & Synonyms

Cl2C6H3CH2CN