Applications

Reacant for:
Preparation of dihydronaphthyridinones as HIV-1 integrase inhibitors¹
Mannich reactions²
Preparation of cyanotetrahydrooxo-ß-carbolines via cyclocondensation reactions³
Asymmetric synthesis of phalarine via stereospecific Pictet-Spengler cyclocondensation and traceless chirality transfer from L-tryptophan⁴
Synthesis of functionalized diarylpyrrolizines as inhibitors of microsomal prostaglandin E2 synthase-1 (mPGES-1) and 5-lipoxygenase (5-LOX)⁵
Synthesis of (±)-phalarine with the rearrangement of an azaspiroindolenine and Gassman oxindole preparation as key steps⁶