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tert-Butyl diethylphosphonoacetate

tert-Butyl diethylphosphonoacetate chemical structure
CAS Number27784-76-5
FormulaN/A
Mol. Weight252.24 g/mol

What is tert-Butyl diethylphosphonoacetate?

tert-Butyl diethylphosphonoacetate is a chemical compound with CAS number 27784-76-5. It is used in various industrial and research applications.

Applications

Reactant for:
• Preparation of ydroxymethylated dihydroxyvitamin D3 analogs via Wittig-Horner approach, as potential antitumor agents1
• Synthesis of phosphopeptide mimetic prodrugs targeted to Src homology 2 (SH2) domain of signal transducer and activator of transcription 3 (Stat 3)2
• One-pot synthesis of the DPP4-selective inhibitor ABT-341 by a four-component coupling mediated by a diphenylprolinol silyl ether3
• Bicyclic triaminophosphine-promoted stereoselective synthesis of a,ß-unsaturated esters, fluorides, and nitriles from aldehydes and ketones using Wadsworth-Emmons phosphonates4
• Preparation of amidopropenyl hydroxamates as human histone deacetylase (HDAC) inhibitors5

sulfate (SO42-): ≤100 mg/kg

Specifications

Linear Formula

(C2H5O)2P(O)CH2CO2C(CH3)3
Co: ≤50 mg/kg

Molecular Weight

252.24 g/mol

Assay/Purity

95%

Boiling Point

100-103 °C/1.5 mmHg(lit.)

Density

1.074 g/mL at 25 °C(lit.)

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