(+)-Thalidomide
(+)-Thalidomide
What is (+)-Thalidomide?
(+)-Thalidomide is a chemical compound with CAS number 2614-06-4 and molecular formula C13H10N2O4. It is used in various industrial and research applications.
Applications
Thalidomide has been used to study its teratogenic effects in chicken embryos and human embryonic cells. This study reported that thalidomide causes limb defects by stabilizing PTEN, inhibiting the expression of Akt and activating caspase-dependent apoptosis1. Thalidomide has also been used for studying glutathione mediated teratogenic resistance in mouse embryos2.
Specifications
258.23 g/mol
≥98% (HPLC)
DMSO: soluble15 mg/mL, clear
Safety Information
GHS07
GHS08Danger
H302-H360
P201-P308 + P313
Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
3