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Diisopropyl (ethoxycarbonylmethyl)phosphonate

Diisopropyl (ethoxycarbonylmethyl)phosphonate chemical structure
CAS Number24074-26-8
FormulaC2H5O2CCH2P(O)[OCH(CH3)2]2
Mol. Weight252.24 g/mol

What is Diisopropyl (ethoxycarbonylmethyl)phosphonate?

Diisopropyl (ethoxycarbonylmethyl)phosphonate is a chemical compound with CAS number 24074-26-8 and molecular formula C2H5O2CCH2P(O)[OCH(CH3)2]2. It is used in various industrial and research applications.

Applications

Reactant for:
• Preparation of spiroimine ring fragment of spirolides via stereoselective intermolecular Diels-Alder and aza-Wittig cyclization1
• Katsuki-Sharpless epoxidation reaction2
• Preparation of nine-membered diallylic sulfonamides as chiral building blocks3
• Alpha-phosphono lactams for subsequent Wadsworth-Emmons olefination, and Suzuki coupling reactions to yield diverse pyrrolidinone compounds4
• Synthesis of galactosylceramide analog that induces Th1-biased responses in human (NKT) cells5
• Stereoselective total synthesis of the ionophore antibiotic zincophorin (M144255)6

Specifications

Linear Formula

C2H5O2CCH2P(O)[OCH(CH3)2]2

Molecular Weight

252.24 g/mol

Assay/Purity

95%

Boiling Point

142-143 °C/11 mmHg(lit.)

Density

1.06 g/mL at 25 °C(lit.)

Safety Information

GHS07GHS07
Signal Word

Warning

Hazard Statements

H315-H319-H335

Precautionary Statements

P261-P305 + P351 + P338

Required PPE

dust mask type N95 (US), Eyeshields, Gloves

WGK Germany

3

Frequently Asked Questions